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KMID : 0939920090410040229
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대한암학회지
2009 Volume.41 No. 4 p.229 ~ p.232
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Mixed Testicular Germ Cell Tumor Presenting as Metastatic Pure Choriocarcinoma Involving Multiple Lung Metastases That Was Effectively Treated with High-dose Chemotherapy
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Lee Sang-Cheol
Kim Kyoung-Ha
Kim Sung-Han
Lee Nam-Su
Park Hee-Sook
Won Jong-Ho
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Abstract
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Choriocarcinoma in the testis is very rare, and it represents less than 1% (0.3%) of all the testicular germ cell tumors. It is a particularly aggressive variant of non-seminoma tumor, which is characterized by a high serum β-HCG level and multiple lung metastases. The optimal management for this disease remains undefined. We report here on a case of choriocarcinoma with multiple lung metastases, and the patient has achieved continuous remission for 2 years after combination chemotherapy of BEP (bleomycin, etoposide and cisplatin) and sequential high-dose chemotherapy with autologous peripheral stem cell rescue.
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KEYWORD
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Neoplasms, Germ cell and embryonal, Testicular choriocarcinoma, High-dose chemotherapy.
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